Nature-inspired nanodiscs for lesion-targeted delivery reprogram macrophages and attenuate established abdominal aortic aneurysms biorxiv.org
BARseq3: a modular system for integrating spatial multi-omics and cellular barcoding in single cells biorxiv.org
Radical cell identity bifurcation in Saccharina embryos coincides with the expression of newly acquired genes. biorxiv.org
Senescent cells induce vascular MHC II to recruit CD4+ T cells and drive inflammation in aging adipose tissue biorxiv.org
Pharmaceutical assessment of low global warming potential alternatives to HFA-134a in a budesonide, glycopyrrolate, and formoterol fumarate pressurized metered dose inhaler biorxiv.org
ATF4 programs proline-dependent immune evasion in β-Catenin-driven hepatocellular carcinoma biorxiv.org
Investigating the Dynamic Relationship Between Anxiety and Spatial Memory Using Autonomous Ecological Momentary Assessment biorxiv.org
Biological foundation models illuminate annotation blind spots in evolutionarily divergent genomes biorxiv.org
Chloroplast genome engineering of potato enables diterpene production without agronomic penalty biorxiv.org
The Chromosome-Scale Genome of Phyllanthus niruri Reveals Candidate Genes and a Putative Biosynthetic Framework for Phyllanthin Formation. biorxiv.org
Highly contiguous reference genome assembly of the endangered Orces blue whiptail Holcosus orcesi biorxiv.org
In silico restriction site analysis of whole genome sequences shows patterns caused by selection and sequence duplications biorxiv.org
Chromosome-level genome assemblies of the red algae Porphyra dioica and Porphyra linearis biorxiv.org
Pangenome reference assemblies reveal the variation and recent activity of human LINE-1 retrotransposons biorxiv.org
Canavanine-based assay for gross chromosomal rearrangements reveals genome instability hotspots and modulating genes in fission yeast biorxiv.org
A weighted multi-trait approach for heterotic grouping of maize inbred lines under Striga infestation and optimum environments biorxiv.org
Reproductive Trade-offs in Caribbean Corals: Plasticity Accelerates While Fragmentation Delays Reproductive Capacity biorxiv.org
Predator adaptation to single prey species yields positive specialization and multiple forms of diversification biorxiv.org
Allometric correlates of heat tolerance in birds: A test using quail breeds with extreme size variation biorxiv.org
Population genomics of nicotinic acetylcholine receptors in Anopheles funestus reveals rapid evolution of the α9 and β2 subunits within a constrained gene family biorxiv.org
Large-scale genomic rearrangements are a potential explanation for reproductive isolation in the Pogonomyrmex dependent-lineage system biorxiv.org
Distribution and heritable shell differentiation among populations of the sole lymnaeid snail across freshwater habitats of southern Patagonia biorxiv.org
Historically Small Population Size Limits Purging of Deleterious Mutations in a Conservation-Reliant Species, the Kirtlands Warbler biorxiv.org
From species-area relationships to biodiversity risk assessment biorxiv.org Biodiversity is commonly summarized by macroecological mean patterns, most prominently the species-area relationship (SAR) linking habitat area to exp
How Demographic Noise Shapes Phenotypic Clusters in Environmental Gradients biorxiv.org Although resources are typically distributed continuously in space, species distributions often organize into discrete clusters.
Analyzing how habitat degradation drives extinction dynamics using physiologically-structured population models biorxiv.org Elucidating how habitat degradation facilitates extinction is critical for effective conservation efforts.
From protection to amplification: Imperfect chytridiomycosis prophylaxis increases infections in wild amphibians biorxiv.org Wildlife vaccination could become a powerful strategy to mitigate disease-induced biodiversity losses, yet many vaccines for wildlife diseases provide
Recreational climbing alters cliff soil chemistry and plant-associated fungal communities biorxiv.org
Evolution of allostery without shape shifting: Internal dynamics drives functional diversification of a transcriptional repressor superfamily biorxiv.org
The Joint Impact of Deleterious Mutations, Dominance, and Gene Flow on Linked Neutral Variation in Structured Populations biorxiv.org
Circadian Clock Programming of Anticipatory Antiviral Immunity Gates Enteric Virus Infection Susceptibility biorxiv.org
Relational biological structure improves fine-mapping of causal GWAS variants under weak signal biorxiv.org
Rapid connectivity alterations of thalamic nuclei during initial learning of goal-directed behaviour biorxiv.org The thalamus is essential for learning, dynamically engaging with other subcortical and cerebral cortex regions throughout the learning process.
Pyramidal-cell-specific hemispheric asymmetry shapes dorsoventral CA1 dynamics during rest and exploratory behavior biorxiv.org
Continuous negative autoregulation fine-tunes dosage-sensitive transcription factor expression to maintain post-mitotic neuron identity biorxiv.org
Noisy information about the environment: A source of individual differences within and across generations biorxiv.org
Dendrite-soma interactions in cultured hippocampal neurons form non-random structural motifs with local presynaptic enrichment and strengthening biorxiv.org