The impact of ankle immobility on sprint cycling performance: Implications for para-cycling classification biorxiv.org
How the Body Shapes the Mind's Eye: Cardiac vagal reactivity predicts visual imagery vividness biorxiv.org
CYCLON is a nucleolar protein that regulates pan-cancer cell fitness through ribosome biogenesis biorxiv.org
Identification of non-covalent inhibitors for the atypical peroxiredoxin PRDX5 as a therapeutic strategy in malignant pleural mesothelioma biorxiv.org
Enhanced Radio-sensitization of Glioblastoma Using a Dendrimer-Based Metformin Nano-formulation through Direct Tumor Suppression and Indirect Immune Modulation biorxiv.org
Electrodiffusion analysis of concentration and voltage changes in thin cylindrical domains using cross-diffusion modelling biorxiv.org
S2F-agent: Skill-grounded agent for Sequence-to-Function computational genomics workflows biorxiv.org
Thoughts-as-Planning: Latent World Models for Chain-of-Thoughts Optimization via Reinforcement Planning biorxiv.org
Granger Sensori-Behavioral Taxonomy of Neuronal Ensemble Activity from Two-Photon Calcium Imaging Data biorxiv.org
Regional distribution of white matter hyperintensity burden in coronary artery disease and links with coronary revascularization procedure biorxiv.org
THERAPEUTIC EFFECTS OF AN INSULIN-LIKE GROWTH FACTOR I SENSITIZER IN TRAUMATIC BRAIN INJURY biorxiv.org
A paradoxical relationship between mitochondrial calcium regulation and retinal ganglion cell degeneration after axon damage biorxiv.org
Computational drug repurposing identifies N-acetylglucosamine as a potential therapeutic compound for CLN3 Batten disease biorxiv.org
Cardiovascular risk gene HDAC9 drives maladaptive vascular remodeling after arterial injury biorxiv.org
A novel pipeline for the validation of manganese chelators for the treatment of manganese overload biorxiv.org
Danish profile of soft rot Pectobacteriaceae; A three-year field sampling study proving several clonal clades of soft rot isolates across diverse locations implicating a common origin biorxiv.org
Evaluating longitudinal ecological models linking scientific production to population-level indicators: a global case study in mental health research biorxiv.org
Genomic, Clinical, and Spatial Predictors of Durable Response to BRAF/MEK Inhibition in BRAF-Mutant Melanoma biorxiv.org
Evaluation of fluorescent proteins for compatibility with STED microscopy systems using two-color spectroscopies biorxiv.org
Improving Variant Effect Prediction by Steering Sparse Mechanistic Features in Protein Language Models biorxiv.org
Electroporation-mediated delivery of protein biosensors for metabolic imaging in differentiated myotubes biorxiv.org
Diffusion-based stimulus optimization reveals functional organization across higher visual cortex biorxiv.org Characterizing the fine-grained functional organization of human higher visual cortex remains a central challenge, as traditional neuroimaging experim
Human-like sequential sound-to-meaning transfer drives artificial speech comprehension biorxiv.org Artificial intelligence has reached a pivotal threshold.
Context-Specific Decoupling and Competing Phenotypes: Transdiagnostic Eye-Tracking Biomarkers of ASD and ADHD During Naturalistic Viewing in a Large Pediatric Cohort biorxiv.org Autism Spectrum Disorder (ASD) and Attention-Deficit/Hyperactivity Disorder (ADHD) show considerable clinical overlap, yet categorical diagnostic boun
Conserved fiber topography of the anterior limb of the internal capsule in treatment-resistant psychiatric patients biorxiv.org Introduction The anterior limb of the internal capsule (ALIC) is a major white matter highway connecting prefrontal cortical (PFC) regions to the thal
PS FAD mutants and γ-secretase inhibition accumulate VEGFR2-derived peptide VCTF1 suppressing brain VEGFR2 dimerization, angiogenesis and neuroprotection. biorxiv.org Efficient cerebrovasculature is vital to neuronal health and cognition and evidence shows most dementia patients have cerebrovascular abnormalities.
Octopaminergic signaling contributes to thermal adaptation to elevation in African honey bees (Apis mellifera) biorxiv.org Adaptation to local environments enables species to thrive in diverse and challenging habitats.
Seeing and smelling mates: multimodal integration and visual gating of chemical cues in female mate-location behavior in the prawn Macrobrachium rosenbergii biorxiv.org
Actin disassembly triggers CNS myelin compaction and wrapping biorxiv.org Compact myelin enables rapid and precise impulse conduction in the vertebrate nervous system.
Macroscale traveling waves link perception, response selection, and vocal production during marmoset vocal interactions biorxiv.org
Coarse-graining metabolic networks via feature learning reveals cross-species growth laws biorxiv.org