Beyond Onset Timing: Longer Sound Envelope Duration Enhances Neural Representation of the Musical Beat biorxiv.org
Auditory Working Memory Mediates the Relationship between Musical Sophistication and Speech-in-noise Perception biorxiv.org
HTRA1 deficiency in COL4A1 mutant hiPSC-derived astrocytes, a convergent mechanism of cerebral small vessel disease biorxiv.org
AN OPTIMIZED AND DRUGGABLE HUMAN KERATINOCYTE AND IPSC-DERIVED SENSORY NEURON CO-CULTURE SYSTEM FOR ATOPIC ITCH biorxiv.org
A region-specific murine intestinal monolayer platform for assessing iron form-dependent transepithelial transport biorxiv.org
Collagen crosslinking and organizational patterns reflect common disease processes in idiopathic pulmonary fibrosis and non-resolving acute respiratory distress syndrome biorxiv.org
PARP1 catalytic domain mutations drive high-level resistance to saruparib while preserving DNA damage response vulnerabilities biorxiv.org
SOCS1 expression in prostate epithelial cells is essential for tissue homeostasis and tumor suppression biorxiv.org
Neuroendocrine-like/EMT dedifferentiation mediates resistance to EGFR inhibitors via the NRG1/HER3 axis biorxiv.org
An assessment of normalization and differential expression methods for miRNA-seq analysis using a realistic benchmark dataset biorxiv.org
Disagreement between demultiplexing methods reveals structured cell quality gradients in multiplexed single-cell data biorxiv.org
Monocyte-Mimetic Nanoprobe Enables Longitudinal MRI of Atherosclerotic Inflammatory Dynamics biorxiv.org
WATER reveals heterochrony of molecular programs underlies developmental failure caused by minor spliceosome inhibition biorxiv.org
Spinal lumen remodeling under the control of Gli signaling mechanically drives roof plate cells extension biorxiv.org
Desmoglein-3 modulates p38MAPK and ERK signaling responses through the mechano-sensitive channel Piezo1 biorxiv.org
Calmodulin requires calcium to be a constitutive component of the spindle pole bodies in fission yeast biorxiv.org
Evaluating non-lethal tissue suitability for telomere length measurement in the Japanese eel biorxiv.org
Impaired lipoprotein secretion by APOE4 leads to lysosomal and mitochondrial dysfunction in human microglia biorxiv.org
Channelrhodopsin Ion Selectivity Determines Mechanisms and Efficacy of Optogenetic Defibrillation in Human Atria and Ventricles biorxiv.org
Pericyte Loss Reprogrammes Capillary Endothelium and Drives White Matter Injury in Small Vessel Disease biorxiv.org
SPECTRA: Spatial Inference for Tractometry Toward Precision Mapping of White Matter Microstructure biorxiv.org
Deep Representation Learning on Whole-Brain Population Dynamics Uncovers Geometrically Separable Neural Codes biorxiv.org
Trajectories of hippocampal subregion development in the first years of life and their association with school-aged episodic memory outcomes biorxiv.org
Behavioral evidence challenges species-specific ocular morphology as a primary constraint on human gaze-following biorxiv.org
Simulating the spectrum, not the syndrome: Large scale individualized modeling of oral reading in stroke aphasia biorxiv.org
Postweaning social isolation induces gene expression alterations and histone modification dysregulations in nucleus accumbens (NAc) neurons biorxiv.org
Maternal high-fat diet drives sex-specific microglia remodeling of serotonergic reward circuits biorxiv.org
Differential maturation in vestibular neuronal groups related to developmental motor reorganization in amphibians biorxiv.org
Inflammation-induced epigenetic memory restores oligodendrocyte progenitor cell regenerative capacity in the aged central nervous system biorxiv.org
Astrocyte immunosuppressive activity in glioblastoma depends on ZEB1 and is counteracted by CXCL14 biorxiv.org
Temporal-to-spatial patterning of embryonic structures can involve active transformation of temporal information rather than direct mapping biorxiv.org
Preserved functions with profound morphological reorganization in human organotypic cultures biorxiv.org Human organotypic slice cultures provide experimental access to adult human neuronal circuits ex vivo, yet it remains unclear whether these networks p
Stage-specific CHI3L1/YKL-40 signaling controls generation of oligodendrocyte precursor cells through IL13Rα2-mediated ferroptosis biorxiv.org
Metabolomic and lipidomic shifts underpin physiological acclimation to thermal stress in the European green crab (Carcinus maenas) biorxiv.org
Climate Gradients and Habitat Discontinuity Structure Genetic Variation in a Spring-Specialist Plant biorxiv.org
Recovery of proofreading-impaired SARS-CoV-2 reveals a mutator phenotype and an ExoN activity threshold for viability biorxiv.org
Phenotypic Analysis of GGDEF/EAL Domain Protein Function in Phytopathogenic Pantoea ananatis biorxiv.org
Learning a reversed bicycle disrupts predictive control and induces interference with the normal bicycle biorxiv.org
ProCAST: A Bioinformatics Suite for Mass Spectrometry-Based Protein Corona Proteomics Analysis biorxiv.org When nanoparticles are exposed to biological fluids, they spontaneously adsorb proteins, forming a protein corona that defines their biological identi
ClaroAI-Bench: Evaluating Agentic Scientific Reproducibility on Real Biomedical Papers biorxiv.org We introduce ClaroAI-Bench, an evaluation suite for measuring AI agents' ability to reproduce computational findings from published biomedical researc