Prospects of zona pellucida glycoproteins as immunogens for contraceptive vaccine pubmed.ncbi.nlm.nih.gov
A synthetic oligonucleotide probe (5'TTCCA 3')n uncovers a male specific hybridization pattern in the human genome pubmed.ncbi.nlm.nih.gov
Sex-dimorphic behaviour development in the human: prenatal hormone administration and postnatal socialization pubmed.ncbi.nlm.nih.gov
Sacrificial mothers: increased matrotrophy is associated with reduced maternal longevity across chondrichthyans and mammals biorxiv.org
Investigating sensorimotor beta burst dynamics as a robust biomarker for graded force modulation in humans biorxiv.org
Chemogenetic Inhibition of the Cortical Amygdala Reduces Alcohol Intake and Restores Thalamic Connectivity in Dependent Female Mice biorxiv.org
The Lower γ Region Ensures Unidirectional Rotation and Torque Generation in the Latter Half of the 80° Substep of F1-ATPase biorxiv.org
Generative Chemistry Platform for Small Molecules Targeting RNA: A Case Study for Chemical Optimization biorxiv.org
Temporal Structure of Environmental Noise Controls the Localization and Tracking of Populations of Chemotactic Microorganisms biorxiv.org
Evaluating β-glucanases as cell wall-permeabilising agents against Phytophthora agathidicida oospores biorxiv.org
A genome-wide RNAi screen identifies host cell cycle regulation as a determinant of Orientia tsutsugamushi infection biorxiv.org
Epigenetic splicing regulation of hTERT mediated by hTAPAS biorxiv.org Telomerase activity is primarily controlled by expression of the catalytic subunit hTERT, yet the mechanisms coordinating its transcriptional and post
The gut microbiota metabolite Urolithin A mitigates JAK signaling to suppress cytokine-mediated autoimmune diseases biorxiv.org Aberrant activation of type I interferon (IFN-I) is closely related to the development of autoimmune diseases.
Sleep Spindle-Locked Targeted Memory Reactivation Enhances Declarative Memory Consolidation biorxiv.org Study Objectives: Sleep spindles are implicated in memory consolidation.
Aging selectively impairs how peripheral vision calibrates anticipatory postural responses to object motion biorxiv.org Anticipatory postural adjustments (APAs) scale with velocity of approaching objects, with scaling magnitude depending on whether the moving object is
Improved model representation of the photosynthetic light reactions reduces estimates of global gross primary productivity biorxiv.org The assimilation of carbon dioxide by plants can be predicted by the Farquhar, von Caemmerer and Berry model of photosynthesis.
Transient uncoupling of the Suc-Tre6P-SnRK1 nexus during salt stress associates with biphasic metabolic reprogramming and root plasticity biorxiv.org Soil salinization threatens global agriculture reducing yields, yet the metabolic signals controlling salt-sensitive root plasticity in alfalfa remain
A graph-based pangenome reveals the genetic basis of climate-resilient and horticultural traits in pear biorxiv.org Climate change poses an increasing threat to the cultivation of deciduous fruit trees, placing greater demands on modern pear breeding.
Somatic-to-germline transmission of horizontally acquired extrachromosomal circular DNA in Brassica graft chimeras biorxiv.org Whether somatically acquired traits can contribute to heritable variation has remained an open question in plant biology for over a century.
Endoplasmic Reticulum Associated Lipolysis Regulates Hepatic Fat Synthesis and Turnover biorxiv.org Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is characterized and initiated by the excessive accumulation of triacylglycerols (TG)
Targeting an RNA Editor to Impede H3K27M+ Pediatric Gliomas biorxiv.org Diffuse midline glioma (DMG) is a lethal pediatric brain tumor with no curative therapies.
Tumor Protein D54 (TPD54) regulates intracellular protein trafficking, cellular function and disease progression in melanoma biorxiv.org
Tumor-associated tissue-resident macrophages drive pancreatic cancer progression through IGF1-IGF1R signaling biorxiv.org The specific contribution of tissue-resident macrophages (TRMs) to pancreatic ductal adenocarcinoma (PDAC) progression remains unclear.
Integrative Genomic, Single-Cell, and Functional Profiling of the CD48-CD244 Axis and NK-Cell Dysfunction in Multiple Myeloma biorxiv.org Multiple myeloma (MM) orchestrates immune evasion by subverting natural killer (NK) cell function.
Maturation-dependent structural dynamics and nanomechanical properties of dengue virus revealed by high-speed AFM and 3D force mapping biorxiv.org Although the maturation state of dengue virus (DENV) particles is a key determinant of their infectivity, maturation is unusually inefficient.
High-Speed AFM Reveals Ligand-Dependent Supramolecular Switching of Human Phosphofructokinase-1 biorxiv.org
Identifying Context-Specific Cell-Cell Interaction Genes Without Ligand-Receptor Databases from Spatial Transcriptomics biorxiv.org
Task-Specialized Protein Language Models Decode the Sequence Grammar of Post-Translational Modification Sites biorxiv.org
MurineCyto-Det: A High-Resolution Murine BALF Cytology Dataset for Leukocyte Segmentation and Detection biorxiv.org
Genomic signatures of selection in Anopheles funestus reveal shared and population-specific adaptive variation across African populations biorxiv.org
Tracking malaria parasite lineages through de novo mutations in highly related Plasmodium falciparum genomes biorxiv.org
NATURAL VARIATION IN RADIOTOLERANCE IS ASSOCIATED WITH DIFFERENCES IN INNATE IMMUNE ACTIVITY AND S-PHASE TRANSCRIPTION IN DROSOPHILA MELANOGASTER biorxiv.org Organismal tolerance of ionizing radiation is a complex trait whose genetic basis has been studied extensively, in large part due to its significance
Gluconeogenesis and glycogen metabolism in the epidermis and endoderm of Xenopus tropicalis embryos and larvae. biorxiv.org
Ectopic hAMH-driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes biorxiv.org
HS3ST1 regulates pulmonary inflammation and is a determinant of clinical outcomes after trauma and hemorrhagic shock biorxiv.org
Decoding murine corneal epithelial specification and homeostasis by single-cell spatial transcriptomics with scRNA-seq enrichment biorxiv.org
Microglia-derived extracellular vesicles attenuate acute α-synuclein induced astrocyte inflammation biorxiv.org
StabCell: Stability selection for clustering and marker detection in single-cell RNA sequencing biorxiv.org