The elusive resistome: a global comparison reveals large discrepancies among detection pipelines biorxiv.org Identifying antibiotic resistance genes (ARGs) from metagenomic data is critical for studying antimicrobial resistance across microbial communities an
Specificity Profiling of the RhoGEF Domain of EhFP10 with EhRho GTPases Involved in Cytoskeleton Remodeling biorxiv.org The Rho family of small GTPases plays a critical role in regulating actin cytoskeleton dynamics during endocytic processes in E.
Extremely low effective population size in a captive-bred population: partial mitigation through management practices biorxiv.org Effective population size (Ne) is a critical parameter for evaluating the evolutionary and persistence potential of endangered populations and for des
Effects of cross-generational inbreeding and Wolbachia infection on sex ratio and life-history traits in parthenium beetle biorxiv.org Sex ratio is a key demographic parameter shaping population dynamics and evolutionary trajectories.
Cyst-type epithelial heterogeneity shapes therapeutic responsiveness in ADPKD biorxiv.org Autosomal dominant polycystic kidney disease (ADPKD) exhibits substantial interpatient variability in disease course and therapeutic response, but the
Single-type neuron transcriptomics uncovers cell-type-specific regulators of host defense in Caenorhabditis elegans biorxiv.org
G4 Eurasian avian-like H1N1 swine influenza viruses exhibit enhanced pathogenicity potential in mice and pigs biorxiv.org Currently circulating swine influenza viruses (SIVs) mainly include H1N1, H1N2, and H3N2 subtypes.
Co-expression of IBDV VP2 and H9N2 HA by recombinant HVT induces high protection against both pathogens in chickens biorxiv.org Infectious bursal disease virus (IBDV) and H9N2 avian influenza virus (AIV) are significant global threats to poultry health and production.
Molecular cloning of a novel, nervous system-specific RGS6 isoform lacking canonical G protein regulatory effects and with dominant negative actions biorxiv.org
C9orf72-associated G4C2 hexanucleotide repeat expression in Drosophila mushroom bodies causes age dependent TDP-43 pathology and dementia relevant phenotypes mediated in part by the glypican Dlp/GPC6 biorxiv.org
Differentiating filter-induced oscillations from physiological stimulation-evoked potentials in intracranial recordings biorxiv.org
Small extracellular vesicles mediate the antihyperalgesic effect of bone marrow stromal cells: the role of "priming" biorxiv.org
Quantitative Analysis of External Urethral Sphincter Stimulation Parameters for Modulating Urinary Output biorxiv.org
Dynamical Systems-Constrained Metabolic Modeling Enables Forecasting of Host-Microbiome Dynamics biorxiv.org
Post-translational modification fidelity of recombinant human lactopontin expressed in Kluyveromyces lactis biorxiv.org
Spatially Resolved Banff Tubulitis and Glomerulitis Scoring in Kidney Allograft Biopsies via Artificial Intelligent-Based Structure Segmentation and Spatial Transcriptomics biorxiv.org
Corpus-wide causality: Algorithm design & application for aggregating gene-disease causal evidence biorxiv.org
Unified sampling framework and experimental benchmarking of sequence- and structure-based protein models biorxiv.org
Crude Fucus vesiculosus fucoidan demonstrates superior SARS-CoV-2 antiviral activity compared to its pure form: binding kinetics and functional studies biorxiv.org
Reinforcement influences the ability of cryptic female choice to exert conspecific sperm precedence in hybridizing Atlantic salmon (Salmo salar) and brown trout (Salmo trutta) biorxiv.org
From Growth Faltering to Recovery: Gut Microbial and Body Composition Signatures of Early Childhood Malnutrition Phenotypes biorxiv.org
Postbiotic Binding of Micro- and Nanoplastics: In Vitro Intestinal Epithelial Protection and Proof of Concept in the Human Mouth biorxiv.org
The enteroviral protease target LSM14A operates outside of P-bodies to augment antiviral innate immunity biorxiv.org
Global Proteome Remodelling in Rhodococcus jialingiae RS1 to Decipher its Plant Growth-Promoting and Biofertilizer Properties: Gene Identification for Transgenics biorxiv.org
Plasmodium falciparum derived extracellular vesicles reprogram host MAP kinase signalling cascade to promote cytoadherence biorxiv.org
Large-scale activity analysis of gut prophages reveals significantly active lineages in the human gut biorxiv.org
A standardized, surgically relevant map of organ-spesific branch emergence in the human vagus nerve biorxiv.org
Differential evolutionary and ecological patterns in eye loss between parallel visual systems in spiders biorxiv.org
Optical single-channel recording of CRAC channels with HaloTag and a Ca2+-sensitive ligand biorxiv.org
Early-life mucosal T cells direct intestinal stem cell fate via a coordinated developmental program biorxiv.org
High-resolution spatial profiling identifies disease-specific molecular architecture in palmoplantar pustulosis biorxiv.org
Characterization of two lytic bacteriophages isolated from urban surface water in Romania targeting multidrug-resistant Escherichia coli biorxiv.org
Loss of 7-Dehydrocholesterol Reductase-mediated cholesterol biosynthesis activates IRF3 and inhibits control of Mycobacterium marinum infection biorxiv.org