Induction and <i>in silico</i> staging of human gastruloids with neural tube, segmented somites & advanced cell types biorxiv.org
In toto analysis of multicellular arrangement reduces embryonic tissue diversity to two archetypes that require specific cadherin expression biorxiv.org
Self-organization of embryonic stem cells into a reproducible embryo model through epigenome editing biorxiv.org
Spatiotemporally Resolved Transcriptomics of Developing Placenta Reveals Mechanisms of Embryonic Lethality doi.org
ITU and Developmental Biology: A Single-Axiom View of Zygote-to-Adult Cell Expansion, Waddington Landscape, Yamanaka iPSC, Hox Colinearity, Morphogen Gradients, Turing Patterns, Organoids, Regeneration, Aging Hallmarks, and Teratology — Block B 4/? doi.org
ITU and Developmental Biology: A Single-Axiom View of Zygote-to-Adult Cell Expansion, Waddington Landscape, Yamanaka iPSC, Hox Colinearity, Morphogen Gradients, Turing Patterns, Organoids, Regeneration, Aging Hallmarks, and Teratology — Block B 4/? doi.org
Challenging the Astral <sup>™</sup> mass analyzer - up to 5300 proteins per single-cell at unseen quantitative accuracy to study cellular heterogeneity biorxiv.org
Transgene-Free Ex Utero Derivation of A Human Post-Implantation Embryo Model Solely from Genetically Unmodified Naïve PSCs biorxiv.org
Manipulating Embryogenesis and Testing for Potential: Two Real Problems for the Regulation of Stem Cell-based Embryo Models doi.org
Reconstituting epiblast–extraembryonic endoderm interactions restores anterior–ventral patterning in mouse stem cell–based embryo models biorxiv.org
Meditation Styles Are Highly Discriminable from EEG at the Subject Level With Limited Generalization Across the Population: A Machine-Learning Study biorxiv.org
GLP-1 analogs restore inflammatory, mitochondrial and intercellular signaling networks in the SncaG51D/G51D knock-in mouse model of Parkinson's disease biorxiv.org
A Comparative Evaluation of Structural MRI Foundation Models for Brain Age Regression and Sex Classification biorxiv.org
Tumoral Switch in NUMB splicing changes essential transcription pathways and induces malignant properties in tumour cells biorxiv.org
Elongin B orchestrates chromatin and transcriptional programs in H3K27M-mutant diffuse midline glioma biorxiv.org
Multisite Evaluation of an Amplification-based Nanopore Sequencing Solution to Analyze Challenging Clinically Relevant Variants in Genes Associated with Hereditary Diseases biorxiv.org
Computational drug repurposing identified Artemisinin and Mebendazole as potential inhibitors of virulence-associated proteins SKSR and essential kinases CpCDPK1 of Cryptosporidium parvum biorxiv.org
tRNA-derived fragments are elevated in the aging brain and may contribute to neurodegeneration biorxiv.org
Systems-Informed prioritization of Exosomal Protein Candidates in TNBC Identifies an ECM Invasion Module and Nominates Agrin as a High-Priority Target biorxiv.org
Are dumbbell stomata unique? Diversified developmental trajectories in sedges and grasses result in partially convergent stomata biorxiv.org
The Prion-Like Properties of the INO80 Chromatin Remodeler Regulate Metabolic Gene Expression biorxiv.org
Immunometabolic Remodeling of Perivascular Adipose Tissue in Murine Lupus: Implications for Lupus Vasculopathy biorxiv.org
Aortic valve stenosis promotes pathological shear stress-dependent epigenomic dysregulation in circulating T cells. biorxiv.org
Developmental diversification re-patterns basal antiviral immunity across plant cell types. biorxiv.org
RAP2.3 is required for MYB51 and SIGMA3 expression during the response of Arabidopsis thaliana to multifactorial stress combination biorxiv.org
Cavalcade-Mediated Resistance Alters Tomato-Root-Knot Nematode Interactions and Limits Nematode Infection biorxiv.org
Functional Analysis of cha Genes Identifies ChaC as a Glutathione-Degrading Enzyme Rather Than a Sodium Transport Regulator biorxiv.org