Brain2voice 2.0: High-performance voice synthesis brain-computer interface biorxiv.org 2026-07-06 Brain-computer interfaces (BCIs) offer a promising solution to speech loss due to neurological injury by decoding intended speech directly from brain
Sex differences in brain metabolism assessed with whole-brain magnetic resonance spectroscopic imaging biorxiv.org 2026-07-06 Sex differences in brain disorders span age at onset, symptom profiles, disease course and treatment response, and may partly reflect underlying diffe
Frontal Eye Field Leads a Distributed Oculomotor Circuit for Abstract Categorical Decisions biorxiv.org 2026-07-06 Flexible decisions require the brain to transform sensory evidence into abstract, task-relevant variables and then into actions.
Representations of active grasp maintenance emerge during reach-grasp-carry learning in mouse motor cortex biorxiv.org 2026-07-06 Object manipulation is a dexterous behavior requiring ongoing sensorimotor coordination to establish and maintain a grasp during consecutive movements
Maternal defense against intruders changes her subsequent maternal behavior and neural circuitry biorxiv.org 2026-07-06 Although female rats are typically less aggressive than male rats, lactating females will vigorously defend their nests and pups against an intruder.
Neurokraken: A fully flexible, open-source, python-based neuroscience behavior platform biorxiv.org 2026-07-06 A major challenge in behavioral neuroscience is the lack of a unified software framework capable of implementing diverse paradigms across species and
Delaying the onset of aided target recognition highlights allows for a more dispersed allocation of overt attention biorxiv.org 2026-07-06 Visual search is a critical component of many professions such as military operations, baggage screening, and radiology.
Temporal Processing during Decision Making under Uncertainty. biorxiv.org 2026-07-06 Time perception and decision-making are interrelated processes that are critical to much of human and animal behavior.
Anterior insula activity increased by cued risky wins in healthy volunteers biorxiv.org 2026-07-06 Audiovisual cues ("bells and whistles") are ubiquitous in commercial gambling products.
Contextualized phenovectors reveal a Drosophila serotonergic circuit controlling satiety biorxiv.org 2026-07-06 Distinguishing whether a neural circuit genuinely controls a holistic behavioral state, rather than merely producing isolated effects, is a central ch
The Role of Visual Imagery in Face Recognition and Confidence Revisited: New Evidence from Aphantasia, Sampling Context Effects, and a Meta-Analysis biorxiv.org 2026-07-06 The absence of voluntary visual imagery, known as aphantasia, offers a unique lens into the role of visual imagery in visual memory processes such as
Swung and spun in weightlessness : Evidence of immediate canalar underdetection of rotations in parabolic flight biorxiv.org 2026-07-06 Despite extensive research on vestibular function in microgravity, particularly during orbital and parabolic flight exposure, several gaps remain rega
The membrane distal domain of CD16a allosterically regulates NK cell ADCC biorxiv.org 2026-07-06 Antibody-dependent cellular cytotoxicity (ADCC) by natural killer (NK) cells is mediated by the activating IgG receptor CD16a (Fc{gamma}RIIIa), yet th
Historical contingency shapes zebrafish host-microbiome responses to a subsequent biotic challenge biorxiv.org 2026-07-06 Environmental change exposes ecosystems, including host-associated microbiomes, to stressors that occur repeatedly and in sequence, yet it remains unc
Lack of co-ordination of stomatal, hydraulic and leaf browning traits in 16 perennial Australian grass species of differing climate origins biorxiv.org 2026-07-06 Grasslands are vulnerable to increasing drought with global warming, but process-based models lack the mechanistic knowledge required to predict the m
Distance-to-optimum biological drift as a new framework for interpreting routine laboratory results: a benchmark against Reference Change Values across 62 routine biomarkers biorxiv.org 2026-07-06 Background: We propose the biological drift framework for the interpretation of biological test results: a z-score-like framework based on optimized a
Development of a metabolomics-based index to monitor dietary effects on chronic inflammation: The Dietary Metabolomics Inflammation Index biorxiv.org 2026-07-06 Background: The Dietary Inflammatory Index (DII) is widely used to assess the inflammatory potential of diet, but it relies on self-reported dietary a
Lateral interactions override nucleotide state in determining FtsZ filament curvature biorxiv.org 2026-07-06 The bacterial tubulin homolog FtsZ assembles into dynamic filaments that form the cytokinetic Z-ring and drives constriction during cell division.
Development and Characterisation of a Versatile Single-Domain Antibody Specific for M1-linked Ubiquitin Chains biorxiv.org 2026-07-06 Ubiquitin signalling is mediated by structurally distinct polyubiquitin chains that encode discrete cellular functions.
E. coli RsmF activity depends on prior modification of 16S rRNA helix 44 biorxiv.org 2026-07-06 Bacterial ribosomal RNA (rRNA) methylations are important for accurate translation.
BoltzMol-1: Towards Reliable Virtual Screening for Fast and Cost-Effective Hit Discovery biorxiv.org 2026-07-06 We present BoltzMol-1, a small-molecule hit discovery pipeline, centered on an optimized version of Boltz-2, explicitly adapted for prospective discov
Spatial Metabolomics by Desthiobiotin Ligase (DESTNI) in Live Cells biorxiv.org 2026-07-06 Proximity labeling has transformed spatial proteomics by enabling compartment-resolved mapping of protein environments in living cells, yet its extens
Intramuscular Delivery of BMP-2 and Increasing Doses of LECT-1 Using Keratin-PEG Gels for Ectopic Tissue Differentiation biorxiv.org 2026-07-06 Producing bone and cartilage in a controlled and localized manner remains a significant challenge in regenerative medicine.
Approaching the limit: Modeling the physiological bounds of playable space in football biorxiv.org 2026-07-06 Pitch control models quantify spatial dominance in football by estimating which player can arrive first at each pitch location, but they treat all pla
PARS: an automated, open-source pipeline for subject-specific finite element head modelling from MRI biorxiv.org 2026-07-06 Converting medical images into anatomically detailed, subject-specific finite element (FE) models is a long-standing bottleneck in brain computational
3D neuroblastoma models expose divergent responses to magnetic hyperthermia and photothermal therapy biorxiv.org 2026-07-06 Purpose: Hyperthermia is emerging as an adjunct strategy in pediatric oncology, yet its translation is limited by poor understanding of how different
Green-synthesized silver nanoparticles enhance Guibourtia tessmannii antithromboinflammatory therapeutic potential biorxiv.org 2026-07-06 Introduction: Thromboinflammation, which represents the pathological interplay between inflammation and thrombosis, is a leading cause of global morta
Fundamental-realized niche contrasts shape multi-scale species coexistence biorxiv.org 2026-07-06 Ecological theory states that the geographic ranges and coexistence of species are determined by fundamental and realized niches - the sets of environ
An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions biorxiv.org 2026-07-06 Short linear motifs (SLiMs) within intrinsically disordered protein regions mediate transient interactions crucial for cell physiology.
OrthoGLMM: Phylogenetic Association Testing for Gene Content and Trait Evolution biorxiv.org 2026-07-06 Motivation: Comparative genome projects can now assemble and annotate hundreds of species, creating an opportunity to test whether species-level trait