Genomic Insights into Bacterial Communities of Coenocytic Algae Using Metagenome Assembled Genomes biorxiv.org 2026-07-19 Coenocytic algae are organisms that undergo karyokinesis without cytokinesis, resulting in multinucleated cells.
Demographic compensation buffers population decline under variable grazing intensities in alpine grasslands biorxiv.org 2026-07-19 Identifying optimal grazing intensities for sustainable population growth is crucial for informing management strategies.
Host insect microRNAs are translocated to an obligate endosymbiont biorxiv.org 2026-07-19 Many insects rely on intimate interactions with bacterial symbionts housed in specialized cells called bacteriocytes.
Temporal ordering of migration increments carries directional memory under MYO10 depletion and collagen exposure biorxiv.org 2026-07-20 Cell migration is commonly summarized by speed, mean-squared displacement, or a single persistence time, although these descriptors discard the order
R-Ras coordinates reciprocal activation of ERK5 and ERK1/2 under single pathway inhibition in melanoma biorxiv.org 2026-07-20 Malignant melanoma is an aggressive cancer driven by aberrant Mitogen Activated Protein Kinase (MAPK) signaling.
Who Funds Open Data Sharing? Analysis of data availability statements in biomedical publications biorxiv.org 2026-07-20 Open data sharing is increasingly mandated by research funders, journals, and institutions, yet large-scale compliance measurement remains challenging
Prenatal cannabis exposure affects human fetal neurodevelopment: anintegrated multi-omics study biorxiv.org 2026-07-20 Prenatal cannabis use is on the rise, and observational studies suggest that such use results in neurodevelopmental deficits in the offspring.
Morphogenomic description of Cranifera cranifera (Chitwood, 1932) Kloss, 1960 from captive Blaptica dubia Serville, 1838 cockroach biorxiv.org 2026-07-20 Nematodes of the superfamily Thelastomatoidea are found in the digestive system of various arthropods, feeding on their host microbiome.
Stressor identity shapes plasma proteomic and metabolic responses in humans biorxiv.org 2026-07-20 Acute stress triggers rapid physiological adaptations, yet how distinct stress modalities shape the human circulating molecular landscape remains uncl
Structure-guided targeting of the GATAD2A-CHD4 interaction within the MBD2-NuRD complex results in high levels of HbF in adult erythroid cells biorxiv.org 2026-07-20 Fetal hemoglobin (HbF) expression is silenced postnatally in adult erythroid cells.
Cell-resolved transcriptional responses during heat-induced coral bleaching and recovery biorxiv.org 2026-07-19 Coral reefs depend on an intracellular symbiosis between cnidarian hosts and photosynthetic dinoflagellates that is disrupted by ocean warming, causin
Planning in Nonhuman Primates Emerges from Structure Knowledge and is Distinct from Attention, Working Memory, Effort Control, and Learning biorxiv.org 2026-07-19 Forward planning involves mentally simulating future choices.
Bovine-derived H5N1 influenza virus efficiently infects lactating swine via the mammary gland biorxiv.org 2026-07-18 Since 2024, highly pathogenic influenza A(H5N1) viruses have spread extensively among U.S.
A Structurally Defined C12-Alkyl Quaternary Ammonium Compound reduces bacterial burden and biofilm in an infected wound model biorxiv.org 2026-07-18 Background: Methicillin-resistant Staphylococcus aureus (MRSA) remains a common cause of skin and soft tissue infections, and topical agents that comb
Nowhere to Hide: The Effect of Centromere Architecture on LTR Retrotransposon Dynamics biorxiv.org 2026-07-18 Centromere architecture can determine where transposable elements persist, yet its effects on retrotransposon turnover remain poorly understood.
Metabolic inhibition can enable compact physical integration of microbial partners biorxiv.org 2026-07-18 Microbes often generate by-products that inhibit own or consortial growth.
From diet to defense: serpin duplication and gene-expression evolution as putative contributors to poison-frog alkaloid sequestration biorxiv.org 2026-07-18 Diverse organisms use toxins as antipredator defenses.
Discovery and genomic characterization of a novel wild clownfish hybrid from the Philippines biorxiv.org 2026-07-18 Hybridization is widespread among marine fishes and can contribute to adaptation, diversification, and the generation of novel phenotypes.
Phasing of the 'Wonderful' Pomegranate Genome Using Haploid DNA Extracted from Pollen Grains biorxiv.org 2026-07-18 The scientific and commercial interest in pomegranate (Punica granatum L.) cultivation has increased noticeably during the last two decades.
Genomic insights into the karyotypic radiation of a narrow endemic holocentric plant Carex helodes biorxiv.org 2026-07-18 Holocentric chromosomes allow rapid genome changes through chromosomal rearrangements such as fissions, fusions, inversions or translocations.
scWeave: A deep learning model that bidirectionally translates between gene expression and chromatin structure at single cell resolution biorxiv.org 2026-07-18 Chromatin structure and gene expression are intimately linked, yet characterizing how the two covary has proven challenging, primarily because the two
Cellular-Resolution Spatial Transcriptomics Reveals Laminar VSMC Phenotypic Remodeling and a Hypoxic Medial Core in Human Thoracic Aortic Dissection biorxiv.org 2026-07-18 Sporadic ascending aortic dissection (AAD) carries high short-term mortality and long-term morbidity.
Whole-genome resequencing identified loci underwent divergent selection and improved local adaptability in groundnut (Arachis hypogaea) biorxiv.org 2026-07-18 There is an urgent need to expand groundnut genomics knowledge base to improve yield and adaptability in the target environments.
PrimeKG-Plus: a literature-derived expansion of a multimodal precision medicine knowledge graph biorxiv.org 2026-07-18 Biomedical knowledge evolves rapidly, yet most disease-centered knowledge graphs remain unchanged after publication.
User-friendly transcriptomic data analysis with ArrayAnalysis biorxiv.org 2026-07-18 Transcriptomic profiling has become a cornerstone of modern biomedical research.
Survey and Evaluation of Applied Containerization Practices in Bioinformatics biorxiv.org 2026-07-18 Containerization enables portable, reproducible, and scalable scientific computing.
Direct detection of alternative DNA conformations with long-read sequencing and machine learning approaches biorxiv.org 2026-07-18 Progress has been made in identifying G-quadruplexes (G4s) and other non-canonical (non-B) DNA structures in live cells.
Long-read transcriptomics highlights venom gland specialization and Inhibitor Cystine Knot (ICK) rich toxin diversity in Philippine tarantulas biorxiv.org 2026-07-18 Animal venoms are a rich source of bioactive molecules, yet their diversity remains incompletely characterized in many species.
Cooperativity and Conformational Rearrangements in Protein-Protein and Protein-Ligand Interactions biorxiv.org 2026-07-18 Streptavidin-biotin, avidin-biotin interactions are classical models for protein-ligand binding, yet the energetic changes accompanying biotin binding
Sustained loss of Pptc7 triggers variable skeletal muscle dysfunction and diminished body mass through dysregulation of BNIP3 biorxiv.org 2026-07-18 The mitochondrial phosphatase PPTC7 is required to sustain mammalian metabolism, as its global knockout (KO) triggers hypoketotic hypoglycemia and per