Rediscovery of the eucerine bee Xenoglossa cressoniana in Texas biorxiv.org 2026-06-01 Xenoglossa cressoniana, also known as Tetraloniella cressoniana or Xenoglossodes cressoniana, is a eucerine bee known mainly from the US Great Plains.
Schwann Cell Mapping and Characterization in Bone of Different Embryonic Origins biorxiv.org 2026-06-01 Schwann cells (SCs) provide support for nerves throughout the body.
Species- and Topic-aware Representation Learning for Antimicrobial Peptide Discovery biorxiv.org 2026-06-01 Antimicrobial resistance poses a major global health challenge, necessitating efficient strategies to discover potent antimicrobial peptides (AMPs).
Cost-Effective Purification of Endotoxin-Free LIF, IL-2, and IL-33 biorxiv.org 2026-06-01 We describe a cost-effective Escherichia coli (E. coli)-based platform for producing endotoxin-free cytokines.
Uncovering phenotypic diversity and cell-type-specific prefrontal cortex calcium dynamics in rat fentanyl self-administration biorxiv.org 2026-06-01 BACKGROUND: The proliferation of the potent synthetic opioid fentanyl has exacerbated the ongoing crisis of substance use disorder and associated over
Preclinical Safety Evaluation of Human Lactoferrin Alpha (Effera(R)) biorxiv.org 2026-06-01 The preclinical safety of human-equivalent lactoferrin alpha (heqLF; effera(R)), produced by Komagataella phaffii, was evaluated to support its use as
Nano- and microplastics in pediatric tonsil tissue: bioaccumulation, distribution, and immunomodulatory effects in human lymphoid aggregate organoids biorxiv.org 2026-06-01 Nano- and microplastics (NMPs), by-products of the fragmentation and degradation of plastic products, are ubiquitous environmental contaminants, yet t
Prevotella stercorea links gut microbiome ecology to respiratory infection protection through a host-context-dependent, species-autonomous pathway biorxiv.org 2026-06-01 Using a longitudinal cohort of 633 Gambian children (IHAT-GUT, NCT02941081), we resolve two mechanistically distinct ecological pathways linking Prevo
Selective Activation of Nerve Fiber Subpopulations with Intrafascicular Stimulation biorxiv.org 2026-06-01 Background: Peripheral nerve stimulation (PNS) is most effective when specific nerve fiber subpopulations are activated, while minimizing off-target a
Assessing and Optimizing Low-Frequency Somatic Mutation Detection: A Multi-Platform High-Throughput Sequencing Perspective biorxiv.org 2026-06-01 The availability of multiple commercial short-read sequencing platforms necessitates systematic cross-platform performance comparisons, particularly f
A Multi-Epitope Vaccine Design for Human Pasteurellosis using Outer Membrane β-barrel Proteins of Pasteurella multocida biorxiv.org 2026-06-01 Pasteurella multocida is a facultative anaerobic, Gram-negative coccobacillus that causes pasteurellosis in companion animals (cats and dogs), livesto
Trustworthy ML/AI for Aging Clocks: Preventing Systematic Prediction Bias in Biological Age Estimation biorxiv.org 2026-06-01 Machine learning (ML)- and artificial intelligence (AI)-based aging clocks are increasingly used to quantify physiological and molecular aging from om
Controlled delivery of iNOS antagonist, 1400W, for synergistic breast cancer therapy biorxiv.org 2026-06-01 Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks effective targeted therapies and is frequently associated wi
A field method to optimize dried blood spot sampling for mercury biomonitoring biorxiv.org 2026-06-01 Abstract 1. Heavy metals are pervasive environmental contaminants that can impair the health of organisms globally.
Functional characterization and classification of mechanosensitive bladder afferents biorxiv.org 2026-06-01 Normal urinary bladder function relies on afferent fibers that detect and integrate mechanical and chemical cues related to bladder distension.
Globin digest and its constituent peptides promote skeletal muscle hypertrophy and enhance physical performance biorxiv.org 2026-06-01 Globin digest (GD), an acidic protease hydrolysate of hemoglobin, has been recognized for its anti-obesity and glucose-modulating effects; however, it
C4 photosynthetic pathway fluxes in transgenic rice plants biorxiv.org 2026-06-01 Most land plants photosynthesize using the ancestral C3 pathway, in which ribulose bisphosphate carboxylase/oxygenase (Rubisco) fixes CO2 into 3-carbo
Osmotic-stress-inducible nuclear condensates restrict gene inducibility biorxiv.org 2026-06-01 Plants, as sessile organisms, have developed various mechanisms to respond to environmental stress conditions.
Structure determination and dual targeting of a plant TACO1 identifies its ancient role as an organelle translation regulator biorxiv.org 2026-06-01 Ribosome stalling caused by polyproline (PPs) motifs is common.
Anterior default mode brain state dynamics predict depressive symptom severity before and during TMS treatment biorxiv.org 2026-06-01 Transcranial magnetic stimulation (TMS) targeting the left dorsolateral prefrontal cortex is known to progressively reduce symptoms of depression.
Grooming as a window into the post-stress recuperative process biorxiv.org 2026-06-01 Alterations in rodent self-grooming have been used to model various facets of neuropsychiatric illness.
Hindmarsh-Rose neuronal network with spike-timing-dependent plasticity demonstrates coordinated reset neuromodulation biorxiv.org 2026-06-01 Computational models of brain structures impacted by Parkinson's disease are useful for exploring potential therapies.
A model of schema learning based on biological dimensionality reduction during sleep biorxiv.org 2026-06-01 Reorganizing learned knowledge into generalized representations and transferring it to future learning are essential aspects of cognition, often descr
Behavioural plasticity in Caenorhabditis elegans navigating dynamic granular environments biorxiv.org 2026-06-01 The mechanisms that steer behavioural plasticity in complex environments remain poorly understood.
Monkey hear, monkey do what? An application of Automated Behavioural Response systems for hypothesis testing in the worlds smallest monkey biorxiv.org 2026-06-01 Observer effects are a frequent problem in animal behaviour studies, particularly when assessing responses to human disturbance.
Ultra-efficient High Resolution 3D Reconstruction of Spatial Omics Data with Neural Transcriptomic Field biorxiv.org 2026-06-01 Biological tissues are inherently three-dimensional (3D) ecosystems where spatial architecture dictates cellular function.
Local mechanical gradients underlie coordinated cascades of epithelial cell-cycle advance biorxiv.org 2026-06-01 Cell division mechanically perturbs the local environment in epithelial tissues, yet whether and how these perturbations propagate to coordinate cell-
Label-free 3D virtual histology of human formalin-fixed paraffin-embedded (FFPE) prostate needle biopsies with propagation-based phase-contrast micro-CT (PBCT) biorxiv.org 2026-06-01 For over a century, the goal of estimating clinical outcome from tumor biopsies has been based on histomorphology of 2D tissue slices that represent a
An Integrative Taste Receptor Links pH and Amino Acids to Sugar Sensing in Bemisia tabaci biorxiv.org 2026-06-01 Phloem-feeding insects execute complex behavioral decisions to secure essential nutrients from a diet characterized by nitrogen scarcity and severe os
Multiscale intraspecific variation and coordination of hydraulic traits in silver fir biorxiv.org 2026-06-01 - Intraspecific variability in hydraulic and morphological traits may alter projections of forest vulnerability to climate change.