Multiscale active transport driven by gravitactic bioconvection promotes resilience in algal blooms biorxiv.org 2026-06-23 Algal blooms are frequently dominated by motile species1,2 whose vertical migration enhances resource acquisition and bloom development3,4.
A mathematical model for the efficient control of the New World screwworm biorxiv.org 2026-06-23 An outbreak of New World screwworm has recently been spreading across Mexico, after more than 30 years of absence.
Acoustic detection of a rarely vocalising invasive mammal from sparse data biorxiv.org 2026-06-23 1. Monitoring and limiting the spread of invasive species on islands requires efficient detection and population estimation methods.
The MosAICo ecosystem: bridging the taxonomic gap in vector surveillance with real-time entomological artificial intelligence biorxiv.org 2026-06-23 Mosquito-borne diseases represent an escalating global health threat, driven by climate change, urbanization, and the spread of invasive vectors into
No silver bullet: Patterns of macrosynteny recapitulate systemic conflicts in the higher-level relationships of the arachnids biorxiv.org 2026-06-23 Rare genomic changes have long been sought by phylogeneticists for their potential to resolve obdurate nodes in the tree of life.
First genetic detection and ongoing eDNA monitoring of the golden mussel (Limnoperna fortunei) in California biorxiv.org 2026-06-23 Here, we report the first genetic confirmation of golden mussels (Limnoperna fortunei) in North America, and the subsequent development, optimization,
Is APOE ε2 always a protective allele? Deviations in Hardy-Weinberg equilibrium in admixed Brazilian elderly individuals biorxiv.org 2026-06-23 The APOE gene is a critical determinant of human healthspan and longevity, with the rare {epsilon}2 allele traditionally viewed as a universal protect
Variation and selection at predicted G-quadruplexes across the human pangenome biorxiv.org 2026-06-23 G-quadruplexes (G4s), non-canonical DNA structures whose sequence motifs occupy approximately 1% of the human genome, are important for myriad cellula
A PLP-Dependent Decarboxylative Mannich Reaction Initiates Construction of the Nonpeptidic Scaffold of Kaitocephalin biorxiv.org 2026-06-23 Kaitocephalin (KCP) is a fungal neuroactive natural product bearing a peptide-like yet nonpeptidic amino acid-derived scaffold in which amino acid-lik
The structure of the lipid II flippase from monoderm bacteria biorxiv.org 2026-06-23 Peptidoglycan biogenesis requires membrane flippases to translocate lipid-linked precursors across the cytoplasmic membrane for processing (1).
Segmental Variability of Bolus-dispersion-induced Myocardial Blood Flow in Quantitative Myocardial Perfusion MRI: A CFD-based Analysis biorxiv.org 2026-06-23 Background: Quantitative dynamic contrast-enhanced myocardial perfusion cardiovascular magnetic resonance (CMR) enables estimation of myocardial blood
Programming T cells for intercellular genome editing biorxiv.org 2026-06-23 Therapeutic genome editing requires delivery of editing molecules to defined cell types, but targeting specificity and efficiency are currently limite
Organoid-in-Bead (OrB): vortex-based compartmentalization enables scalable, high-density intestinal organoid culture biorxiv.org 2026-06-23 Intestinal organoids are powerful in vitro models, but their use in large-scale analyses remains constrained by the low throughput, labor-intensive ha
Particle-Only gECM Wafers Enable Cohesive, ECM-Rich Scaffolds Without Secondary Polymers biorxiv.org 2026-06-23 Granular extracellular matrix (gECM)-based biomaterials commonly contain polymer components to improve scaffold cohesion and handling during fabricati
Cervical spinal cord stimulation disrupts proprioception yet improves voluntary arm reaching biorxiv.org 2026-06-23 Whether proprioception is necessary for upper-limb motor control has been debated for decades.
biomeStat: Using Agentic AI for Scalable Genomic Epidemiology Demonstrated Through End-to-End Analysis of 1,000 Asian Dengue Virus Genomes biorxiv.org 2026-06-23 Genomic epidemiology workflows typically require expert curation of multiple specialized tools, extensive manual parameter tuning, and access to heter
The avian colourscape is disproportionately threatened by species extinctions biorxiv.org 2026-06-23 The impact of projected extinctions on global animal colour diversity remains unknown.
The Dark Ecology Dataset: Measurements of Aerial Biomass in US Weather Radar from 1995 to 2025 biorxiv.org 2026-06-23 The US NEXRAD radar network has monitored the aerosphere over the US and its territories continuously since the 1990s and archived nearly 300 million
Testing the waters of macrophyte biodiversity with multiscale spatial analysis of public lake monitoring data biorxiv.org 2026-06-23 Freshwater monitoring programmes like the European Union's Water Framework Directive (WFD) provide a wealth of data on European lake status, including
TickMapKB: A FAIR Spatial Knowledgebase of Tick Species and Associated Pathogens in India biorxiv.org 2026-06-23 Ticks transmit pathogens across wildlife, domestic animals, and humans, and are therefore considered important vectors under the One Health framework.
Lessening the bottleneck: reduced spatiotemporal overlap between krill fishing vessels and post-fledging chinstrap penguins led to increased apparent survival biorxiv.org 2026-06-23 Fledging is a critical period of a seabird life cycle.
A maximum entropy perspective reveals deviations from steady state during active diversification biorxiv.org 2026-06-23 Ecosystems are rarely at steady state, yet most theory predicting universal biodiversity patterns assumes they are.
Smolt migration in relation to latitude, season and migratory distance biorxiv.org 2026-06-23 Downstream migration and sea entry are periods of high mortality for sea trout smolts and migration timing is a critical aspect of survival.
Ancient origins of alkaloid biosynthesis in medicinal clubmosses biorxiv.org 2026-06-23 The plant kingdom is rich with medicinal natural products that are complex and difficult to access.
A finite element model of pregnancy derived from maternal sonography: effect of uterine and cervical structural properties on cervical mechanical loading biorxiv.org 2026-06-23 Identification and treatment of pregnancies at risk for preterm birth is a central challenge in obstetric research.
Engineering of CAR-less lentiviral vectors via ER retention-mediated CAR blockade biorxiv.org 2026-06-23 Chimeric antigen receptor (CAR)-T cell therapies have transformed the treatment of various tumor types by redirecting and activating T cells against t
Engineering an in vitro spinal column: Manufacturing designs and emerging solutions for producing an axial mechanobiological system biorxiv.org 2026-06-23 The human spine is a complex, coordinated biomechanical system.
Temporal and Regional Circular RNA profiling in a Tauopathy Mouse Model: Implications for Tau Pathology and Neurodegeneration biorxiv.org 2026-06-23 MicroRNAs (miRNA), are non-coding RNA that act as post-transcriptional regulators of gene expression in various organs including the brain where they
Single-molecule insights into DNA gyrase in live bacteria biorxiv.org 2026-06-22 Molecular motors travelling along DNA introduce positive supercoils that present as barriers to replication leading to genome instability.
Thrombospondin-2 deficiency primes the synovial joint for aberrant tissue remodeling and injury response biorxiv.org 2026-06-22 Objective.