Genotype and farm effects on yield and morphology reveal potential for breeding and site selection for sugar kelp biorxiv.org
A new method based on genome alignments provides a highly resolutive target enrichment set for weevils (Coleoptera, Curculionoidea) biorxiv.org
Assessing pollinator community recovery in restored agroecosystems using the recovery debt framework biorxiv.org
Cross-Pipeline RNA-seq Analysis Reveals Core Regulatory Gene Signatures Driving P19 Cell Neurogenesis biorxiv.org
Endothelial YAP/TAZ rewiring under cardiometabolic stress drives sex-divergent vascular remodeling in heart failure with preserved ejection fraction biorxiv.org
The inositol pyrophosphate 5-InsP7 promotes DNA repair by disrupting RAD51 binding to the C-terminus of BRCA2 biorxiv.org
cGAS-STING induced IFN-β acts as a dual regulator of osteoclastogenesis via direct and osteoblast-mediated mechanisms biorxiv.org
Focal and subtle myelin damage in multiple sclerosis-derived post-mortem human brain slice cultures biorxiv.org
Single-cell transcriptomics uncovers chromatin dysfunction in a human TDP-43 proteinopathy model of Amyotrophic Lateral Sclerosis. biorxiv.org
Uncertainty-aware graph representation learning with positive-unlabeled classification for biomarker discovery in peripheral artery disease biorxiv.org
Riemannian Tensor Analysis Identifies a Bifurcation State in the Single-Cell Transcriptomic Landscape of Parkinson's Disease biorxiv.org
Non-canonical role of a PHOSPHATE1 HOMOLOG 2 in suppressing seedling photomorphogenesis via the TOC1-PIF4 module biorxiv.org
Cyclic Peptides Target CAPON and Modulate Cellular Responses under Alzheimers Disease-Relevant Stress biorxiv.org
Optogenetic circuit mapping reveals connectivity and synaptic physiology of T-stellate projections from the cochlear nucleus to the auditory midbrain biorxiv.org
Bridging Neurons to Behaviour: A Generative Neural Engine Mechanistically Rejects the Independent Race Model biorxiv.org
Ascending inputs to inferior colliculus subdivisions reveal pathway-specific hybrid organization in the external cortex biorxiv.org
Computer experimentation on E. coli ammonium transport and assimilation reveals mechanisms for energy coupling, balanced futile cycling, and robust growth biorxiv.org
Efficient Bayesian inference for ordinary differential equation models from experimental data with uncertain measurement times biorxiv.org
Gene regulatory networks define human airway epithelial cell types and their distinct responses to type I interferon biorxiv.org The human airway epithelium (HAE) is composed of diverse cell types that coordinate essential functions and host defenses.
Chorismate and isochorismate turnover reveal hidden dynamics of aromatic metabolism in Arabidopsis biorxiv.org
HAIRpred2: Human Host-Specific Prediction of Antibody-Interacting Residues Using Hybrid Physicochemical and Structural Features biorxiv.org
A transgenic zebrafish for direct optogenetic activation of FGF/ERK signaling biorxiv.org Dynamic FGF/ERK signaling plays key roles in development, regeneration, and disease.
Shared roles and team membership are reflected in functional connectome similarity: Neural evidence from real-world volleyball teams biorxiv.org In task-oriented teams, long-term coordination among specialized roles may contribute to shared patterns of cognition and behavior, yet little is know
Integrated luminescence and phenotypic profiling for drug discovery in a zebrafish model of Marfan syndrome biorxiv.org