Genome-wide computational prediction of miRNAs encoded by influenza A virus (H3N2) predicts target genes involved in pulmonary and antiviral innate immunity biorxiv.org
Environmental impacts on gene expression noise and its relationship with fitness biorxiv.org Genetically identical cells grown in the same environment show variation in gene expression known as expression noise.
Molecular epidemiology of the globally spreading genetic lineage IV of peste des petits ruminants virus biorxiv.org Peste des petits ruminants (PPR) is a highly contagious viral disease of small ruminants caused by the peste des petits ruminants virus (PPRV), which
Functional genomic map of local adaptation in sorghum to guide allele mining biorxiv.org Genomic data from genebanks could be exploited to find alleles adapted to target environments for resilience breeding, but it can be difficult to prio
Navigating a dynamic winterscape: habitat composition and individual variability shape daily movement in wintering common cranes in western India biorxiv.org Background: Wintering migratory birds must balance energetic requirements, resource availability, and disturbance in increasingly human-modified lands
Direct and Indirect Entomological Efficacy of Targeted Indoor Residual Spraying against Aedes aegypti in Iquitos, Peru biorxiv.org Background: Control of Aedes aegypti, the primary vector of dengue and other Aedes-borne viruses, is challenged by insecticide resistance, limited eff
Noise and determinism in Trinidadian guppy population dynamics biorxiv.org Natural populations are often nonlinear and exhibit substantial variability.
Trans-Kingdom dsRNA Sensing: Aspergillus fumigatus Mycovirus Activates MDA5/MAVS Immunity and Limits Allergic Bronchopulmonary Aspergillosis biorxiv.org
Transcript architecture predetermines m6A remodeling and sensory neuron vulnerability in chemotherapy-induced peripheral neuropathy biorxiv.org
Orally Bioavailable SARS-CoV-2 Protease Inhibitors Bearing a Hydroxymethyl Ketone Warhead biorxiv.org
Cooperative antibiotic response in coupled biofilm and planktonic E. faecalis communities biorxiv.org
Mechanistic Insights into TMPyP4 Recognition of the HIV-1 LTR-III G-Quadruplex in Dilute and Protein Condensate Environments Reveal Hidden Dual Binding Modes biorxiv.org
ALS mutations in the TIA1 RNA granule protein have differing effect on low complexity domain fibril formation biorxiv.org
An extracellular vesicle biogenesis-inspired engineering platform for efficient protein delivery and therapeutic base editing biorxiv.org
An N-terminal amphipathic helix governs activity and conformational dynamics of Nramp metal transporters biorxiv.org
Disease-associated mutations in TPM2 alter regulation of actin filament stability and cofilin-dependent dynamics biorxiv.org
Unbiased Long-Read Whole-Genome Sequencing Enables High-Resolution Mapping of Transgene Concatenation and Off-target Genomic Disruption in a Mouse Model biorxiv.org
A Single-Nucleus Transcriptomic Atlas Reveals Cell-Type-Specific Responses to OsHV-1 Infection in the Pacific Oyster biorxiv.org
Long-distance dispersal drives global tropical distributions in a widespread moth lineage (Lepidoptera: Limacodidae) biorxiv.org