A practical evaluation of sampling filtration and preservation of environmental DNA samples for the water column monitoring. biorxiv.org 2026-06-19 Offshore industry still largely relies on traditional approaches for regulatory compliance to environmental impact on the water column.
Warming-induced switches in dominance are built into intraguild predation systems biorxiv.org 2026-06-19 Warming affects food webs globally.
Nutrimental determinants of chronological aging and competitiveness in the snf1Δ Warburg model biorxiv.org 2026-06-19 Cancer, one of the world's leading causes of death, is characterized by a complex metabolic reprogramming that features the Warburg effect as one of i
Full-length structure of the anti-viral and pro-tumor DNA deaminase APOBEC3B biorxiv.org 2026-06-19 Human APOBEC3B (A3B) restricts virus infections by catalyzing the deamination of cytosines to uracils in single-stranded DNA.
SNR Enhancement Considerations for Loop Receive Coils at Ultra-High Fields biorxiv.org 2026-06-19 Purpose: To quantify parasitic losses in ultra-high field (UHF) magnetic resonance imaging (MRI) receive coils and determine how they contribute to th
Vibrational optoacoustic detection of lipid-membrane dynamics enables label-free imaging of cell membrane potential biorxiv.org 2026-06-19 Current technologies to monitor membrane potential are either highly invasive and perturb the integrity of the membrane, use labels that compromise bi
Data-driven gait cycle decomposition based on whole-body coordination dynamics biorxiv.org 2026-06-19 The study of human locomotion has long relied on descriptive frameworks of the gait cycle, which have provided essential insights into the functional
Ultrasound-Based Spatiotemporal Monitoring of Coagulation and Thrombolysis via Speed-of-Sound Shift Imaging biorxiv.org 2026-06-19 Blood clot formation and thrombolysis are dynamic biological processes that play central roles in hemostasis, thrombosis, and thrombolytic therapy.
Embedded transport accelerates interaction-limited biosensing biorxiv.org 2026-06-19 Phenotypic biosensors that measure bacterial viability and antimicrobial susceptibility are essential for rapid infectious disease diagnostics, yet th
Pore-Resolved High-Throughput Quantification of Amyloid Aggregation and Amplification biorxiv.org 2026-06-19 Amyloid fibrils are implicated in a wide spectrum of neurodegenerative and systemic disorders, yet their biological consequences are governed not only
Multidomain triple target capture for navigating complex symbioses biorxiv.org 2026-06-19 Abstract: Amplicon sequencing remains the benchmark technique for characterizing microbial communities, but the limitations of PCR bias and single-loc
Lake ecosystem responses to runoff variability across time and space biorxiv.org 2026-06-19 Inland waters in the Northern Hemisphere are experiencing increased annual runoff due to higher overall precipitation as well as intensified short-ter
Distributions of host heterogeneity in susceptibility show signatures of pathogen geographic structure in an insect baculovirus biorxiv.org 2026-06-19 Segregated variation between populations is a fundamental evolutionary process leading to parasite specialization, yet the resulting impacts on infect
Ubiquitin selective ribosome profiling reveals systematic principles of co-translational quality control biorxiv.org 2026-06-19 Protein biogenesis is a stress- and error-sensitive process that can lead to nascent protein misfolding and aggregation, challenging cellular proteost
Simulation-based Bayesian deep learning enables uncertainty-aware tumor fraction estimation in cell-free DNA biorxiv.org 2026-06-19 Background: Estimating tumor fraction from whole-genome cell-free DNA sequencing is critical for liquid biopsy, but is hampered by weak signals and ba
Intersegmental transfers drive target search in an RNA-targeting CRISPR system biorxiv.org 2026-06-18 Sequence-specific RNA-binding proteins (RBPs) must efficiently locate their targets among a multitude of cellular RNAs.
Buffered sweat microfluidics with AI-enabled translation for clinically actionable blood urea estimation and renal risk stratification biorxiv.org 2026-06-18 Kidney-function assessment relies on blood urea as a clinically informative metabolic marker; however, its dependence on venipuncture and centralised
Exploring the Structural and Functional role of α,β-unsaturated Ketoesters as Anti-Staphylococcal Agents Targeting Glutathione Peroxidase biorxiv.org 2026-06-18 Multiple-drug resistant (MDR) Staphylococcus aureus strains (like methicillin-resistant S.
Stochasticity and Bet Hedging Drive Cryptococcal Capsule Dynamics biorxiv.org 2026-06-18 Cryptococcus neoformans and related species are major human pathogens that cause cryptococcosis, a disease with high mortality and morbidity despite a
MALDI-ToF detection of Leishmania infantum infection in Lutzomyia longipalpis and Nyssomyia neivai biorxiv.org 2026-06-18 Background Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF MS) is widely used for sand fly identification, but
Oxidative stress reshapes diatom-microbiome interactions by shifting benefits from mutualistic to opportunistic bacteria biorxiv.org 2026-06-18 The roles of reactive oxygen species (ROS) as signaling molecules and inhibitors of phytoplankton growth are well documented.
Multidimensional Characterization of Novel Phage UCB24 Targeting Erwinia amylovora biorxiv.org 2026-06-18 This study evaluates the novel bacteriophage UCB24 as an eco-friendly biocontrol agent against Erwinia amylovora, the bacterial pathogen responsible f
Low Shear Modeled Microgravity Induces Unexpected Motility Phenotypes in Salmonella Typhimurium biorxiv.org 2026-06-18 Bacteria routinely exhibit unexpected phenotypic and molecular changes in response to spaceflight and spaceflight-analogue conditions, yet the mechani
Intracellular barriers and receptor masking limit success of a Pseudomonas aeruginosa clinical phage family biorxiv.org 2026-06-18 Bacteriophage therapy is needed to treat antibiotic resistant infections; however, when a clinical isolate resists a given phage, it is often unclear
Enzyme-Linked Cycloaddition Assay (ELCA) for rapid, ultra-sensitive monitoring of secreted sialoglycoproteins biorxiv.org 2026-06-18 Glycosylation of proteins is central to cell signaling, immune function, and pathogen interactions, yet existing methods for monitoring glycan changes
Structure-Based Immunoinformatics Design of a CTB-Adjuvanted Multi-Epitope Mucosal Vaccine Against Helicobacter pylori biorxiv.org 2026-06-18 Background: Helicobacter pylori coloniz the gastric mucosa of nearly half of the global population and is classified as a Group I carcinogen by the Wo
Structure Bioinformatics of Eight Human ATP Synthase Fo Subunits and Their AlphaFold3-Predicted Water-Soluble QTY Analogs biorxiv.org 2026-06-18 Human mitochondrial ATP synthase is an essential rotary motor enzyme that produces most of the cellular ATP through oxidative phosphorylation.
Target DNA-Mediated Plasmonic Coupling and Assembly Kinetics of Gold Nanorods for Label-Free Nucleic Acid Detection biorxiv.org 2026-06-18 DNA-programmed assembly of plasmonic nanostructures provides a powerful route to couple molecular recognition with optical signal generation.
Siphoviridae phage tails co-enrich with ex vivo amyloids biorxiv.org 2026-06-18 Bacteriophages are ubiquitous in the environment and are part of the natural human microbiome.
Solvent accessibility of chlorine-reactive amino acid residues in icosahedral virus structures: A meta-analysis biorxiv.org 2026-06-18 Free chlorine reacts with viral proteins, but the protein structural determinants of viral resistance to chlorine treatment remain poorly understood.